Hi Ken,
It depends how the transport line is connected with production.If the transports are moved from dev to production then make sure you remigrate the dso along with the dependant objects which usually gets deactivated with any change in dso structure .Move all these activated objects related to dso to qa once again .
Before remigrating the activated objects to QA again you can delete the old dso table data at QA by simply going se14 Tx ..Edit-->delete data-->Activate and adjust database.The reason for doing is that
if the old dso has huge number of records then it does not allow the new structure to get adjusted in the database until you reduce the volume of data of the older one resulting in not migrating with the new change of structure.
So this step can be done in QA before remigrating the dso with dependant objects again.
Thanks!
Rohit